node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAK22537.1 | ndk | SynWH7803_0111 | SynWH7803_2388 | Atypical alkaline phosphatase with phytase-like insertion; Contains a 5'-nucleotidase domain, possibly involved in degradation of nucleotide diphosphate sugar. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.430 |
CAK22537.1 | panC/cmk | SynWH7803_0111 | SynWH7803_0474 | Atypical alkaline phosphatase with phytase-like insertion; Contains a 5'-nucleotidase domain, possibly involved in degradation of nucleotide diphosphate sugar. | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.930 |
CAK22537.1 | surE | SynWH7803_0111 | SynWH7803_1713 | Atypical alkaline phosphatase with phytase-like insertion; Contains a 5'-nucleotidase domain, possibly involved in degradation of nucleotide diphosphate sugar. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.938 |
CAK22537.1 | udk | SynWH7803_0111 | SynWH7803_1367 | Atypical alkaline phosphatase with phytase-like insertion; Contains a 5'-nucleotidase domain, possibly involved in degradation of nucleotide diphosphate sugar. | Uridine kinase. | 0.910 |
CAK22970.1 | panC/cmk | SynWH7803_0544 | SynWH7803_0474 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.940 |
CAK24599.1 | dfp | SynWH7803_2173 | SynWH7803_0351 | Predicted transcriptional regulator. | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.927 |
CAK24599.1 | panC/cmk | SynWH7803_2173 | SynWH7803_0474 | Predicted transcriptional regulator. | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.970 |
CAK24707.1 | panC/cmk | SynWH7803_2281 | SynWH7803_0474 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.976 |
dfp | CAK24599.1 | SynWH7803_0351 | SynWH7803_2173 | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Predicted transcriptional regulator. | 0.927 |
dfp | panB | SynWH7803_0351 | SynWH7803_1760 | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.519 |
dfp | panC/cmk | SynWH7803_0351 | SynWH7803_0474 | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.912 |
engA | panC/cmk | SynWH7803_0568 | SynWH7803_0474 | GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.928 |
ndk | CAK22537.1 | SynWH7803_2388 | SynWH7803_0111 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Atypical alkaline phosphatase with phytase-like insertion; Contains a 5'-nucleotidase domain, possibly involved in degradation of nucleotide diphosphate sugar. | 0.430 |
ndk | panC/cmk | SynWH7803_2388 | SynWH7803_0474 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.946 |
panB | dfp | SynWH7803_1760 | SynWH7803_0351 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Coenzyme A biosynthesis bifunctional protein coaBC (DNA/pantothenate metabolism flavoprotein); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.519 |
panB | panC/cmk | SynWH7803_1760 | SynWH7803_0474 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.987 |
panC/cmk | CAK22537.1 | SynWH7803_0474 | SynWH7803_0111 | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Atypical alkaline phosphatase with phytase-like insertion; Contains a 5'-nucleotidase domain, possibly involved in degradation of nucleotide diphosphate sugar. | 0.930 |
panC/cmk | CAK22970.1 | SynWH7803_0474 | SynWH7803_0544 | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.940 |
panC/cmk | CAK24599.1 | SynWH7803_0474 | SynWH7803_2173 | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Predicted transcriptional regulator. | 0.970 |
panC/cmk | CAK24707.1 | SynWH7803_0474 | SynWH7803_2281 | Bifunctional enzyme (pantoate-beta-alanine ligase / cytidylate kinase), cyanobacteria-specific; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.976 |