node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYB_2299 | hisC | CYB_2299 | CYB_0260 | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.800 |
CYB_2299 | trpA | CYB_2299 | CYB_0937 | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.678 |
CYB_2299 | trpB | CYB_2299 | CYB_1508 | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.522 |
CYB_2299 | trpC | CYB_2299 | CYB_2343 | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. | 0.724 |
CYB_2299 | trpD | CYB_2299 | CYB_0050 | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.736 |
CYB_2299 | trpE | CYB_2299 | CYB_0535 | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.880 |
CYB_2299 | trpF | CYB_2299 | CYB_0194 | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:Q56320; match to protein family HMM PF00697; Belongs to the TrpF family. | 0.670 |
CYB_2299 | trpG | CYB_2299 | CYB_2417 | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Anthranilate synthase component II; Identified by match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.949 |
cobD-1 | hisIE | CYB_0897 | CYB_0157 | L-threonine-O-3-phosphate decarboxylase; Identified by similarity to GB:AAC79515.1; match to protein family HMM PF00155; match to protein family HMM TIGR01140. | Histidine biosynthesis bifunctional protein HisIE; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | 0.996 |
cobD-1 | trpA | CYB_0897 | CYB_0937 | L-threonine-O-3-phosphate decarboxylase; Identified by similarity to GB:AAC79515.1; match to protein family HMM PF00155; match to protein family HMM TIGR01140. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.655 |
cobD-1 | trpD | CYB_0897 | CYB_0050 | L-threonine-O-3-phosphate decarboxylase; Identified by similarity to GB:AAC79515.1; match to protein family HMM PF00155; match to protein family HMM TIGR01140. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.519 |
hisC | CYB_2299 | CYB_0260 | CYB_2299 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. | 0.800 |
hisC | hisIE | CYB_0260 | CYB_0157 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidine biosynthesis bifunctional protein HisIE; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | 0.997 |
hisC | trpA | CYB_0260 | CYB_0937 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.655 |
hisC | trpD | CYB_0260 | CYB_0050 | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.519 |
hisIE | cobD-1 | CYB_0157 | CYB_0897 | Histidine biosynthesis bifunctional protein HisIE; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | L-threonine-O-3-phosphate decarboxylase; Identified by similarity to GB:AAC79515.1; match to protein family HMM PF00155; match to protein family HMM TIGR01140. | 0.996 |
hisIE | hisC | CYB_0157 | CYB_0260 | Histidine biosynthesis bifunctional protein HisIE; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.997 |
hisIE | trpA | CYB_0157 | CYB_0937 | Histidine biosynthesis bifunctional protein HisIE; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.678 |
hisIE | trpB | CYB_0157 | CYB_1508 | Histidine biosynthesis bifunctional protein HisIE; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.582 |
hisIE | trpC | CYB_0157 | CYB_2343 | Histidine biosynthesis bifunctional protein HisIE; Identified by match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family. | 0.555 |