STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (436 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.
 
 
 0.995
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.992
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.951
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128.
    
 0.852
cobA/hemD
uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.
 
  
 0.746
CYB_2576
Putative membrane protein; Identified by match to protein family HMM PF01940; match to protein family HMM TIGR00297.
 
      0.656
CYB_1014
Hypothetical protein; Identified by Glimmer2; putative.
       0.645
chlD
Magnesium chelatase, ATPase subunit D; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
   
  
 0.607
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
  
 0.576
CYB_1011
Conserved hypothetical protein.
       0.551
Your Current Organism:
Synechococcus sp. JA23Ba
NCBI taxonomy Id: 321332
Other names: Cyanobacteria bacterium Yellowstone B-Prime, S. sp. JA-2-3B'a(2-13), Synechococcus sp. JA-2-3B'a(2-13)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.