STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHYPA_023207Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (132 aa)    
Predicted Functional Partners:
PHYPA_005833
Predicted protein.
   
 0.989
PHYPA_005636
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.902
PHYPA_030371
Predicted protein; Belongs to the actin-binding proteins ADF family.
   
 0.899
AIP1
Actin-interacting protein 1.
   
  
 0.821
PHYPA_008780
Ubiquitin-like domain-containing protein.
   
 
 0.803
PHYPA_014786
Small ubiquitin-related modifier.
   
 
 0.797
PHYPA_030252
Formin-like protein; Belongs to the formin-like family.
    
 0.752
PHYPA_028136
Formin-like protein; Belongs to the formin-like family.
    
 0.752
PHYPA_023641
Uncharacterized protein.
    
 0.752
PHYPA_021570
Formin-like protein; Belongs to the formin-like family.
    
 0.752
Your Current Organism:
Physcomitrella patens
NCBI taxonomy Id: 3218
Other names: P. patens, Physcomitrella patens (Hedw.) Bruch & Schimp., Physcomitrella patens subsp. patens, Physcomitrium patens, Physcomitrium patens (Hedw.) Mitt.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.