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THI1-1 protein (Physcomitrella patens) - STRING interaction network
"THI1-1" - Predicted protein in Physcomitrella patens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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THI1-1Predicted protein; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance (361 aa)    
Predicted Functional Partners:
PP1S163_26V6.2
Predicted protein (583 aa)
   
   
  0.895
PP1S88_47V6.1
Predicted protein (666 aa)
   
   
  0.780
PP1S402_42V6.2
Predicted protein (664 aa)
   
   
  0.780
PP1S88_151V6.2
Annotation not available (231 aa)
     
      0.667
PP1S24_26V6.1
Predicted protein (224 aa)
     
      0.642
PP1S128_2V6.1
Predicted protein (225 aa)
     
      0.642
PP1S412_17V6.1
RecA (460 aa)
         
  0.597
PP1S2552_2V6.1
Annotation not available (439 aa)
     
   
  0.555
PP1S54_247V6.2
Annotation not available (351 aa)
     
   
  0.533
PP1S25_361V6.1
Predicted protein (476 aa)
         
  0.489
Your Current Organism:
Physcomitrella patens
NCBI taxonomy Id: 3218
Other names: Bryophyta, Bryophytina, Bryopsida, Funariaceae, Funariales, Funariidae, Moss Superclass V, Musci, P. patens, Physcomitrella, Physcomitrella Bruch & Schimp, Physcomitrella patens, Physcomitrella patens (Hedw.) Bruch & Schimp., Physcomitrium patens, Physcomitrium patens (Hedw.) Mitt., bryophytes, mosses
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