Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Predicted protein (558 aa)
Predicted Functional Partners:
Predicted protein (377 aa)
Predicted protein (505 aa)
Ca2+/calmodulin-dependent protein kinase (504 aa)
Predicted protein (259 aa)
Na+ transporter (706 aa)
Predicted protein; Belongs to the glycosyl hydrolase 17 family (382 aa)
annotation not available (1177 aa)
Predicted protein; Belongs to the class-I aminoacyl-tRNA synthetase family (692 aa)
Delta-1-pyrroline-5-carboxylate synthase; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family (757 aa)
Predicted protein; Belongs to the class-I aminoacyl-tRNA synthetase family (1006 aa)