STRINGSTRING
TOP6B protein (Physcomitrella patens) - STRING interaction network
"TOP6B" - Predicted protein in Physcomitrella patens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP6BPredicted protein; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP (692 aa)    
Predicted Functional Partners:
PP1S62_130V6.1
Annotation not available (432 aa)
 
 
  0.987
PP1S14_84V6.1
Predicted protein (227 aa)
 
 
  0.983
PP1S248_24V6.1
Predicted protein (196 aa)
 
 
  0.983
PP1S33_203V6.1
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1397 aa)
   
   
  0.822
PP1S109_208V6.1
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1464 aa)
   
   
  0.822
PP1S101_224V6.1
Predicted protein; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (466 aa)
   
        0.545
PP1S226_21V6.1
Predicted protein (229 aa)
   
        0.526
PP1S407_7V6.2
Predicted protein (482 aa)
   
        0.524
PP1S38_401V6.1
Predicted protein (496 aa)
   
        0.524
PP1S159_135V6.1
Annotation not available (1290 aa)
   
        0.521
Your Current Organism:
Physcomitrella patens
NCBI taxonomy Id: 3218
Other names: Bryophyta, Bryophytina, Bryopsida, Funariaceae, Funariales, Funariidae, Moss Superclass V, Musci, P. patens, Physcomitrella, Physcomitrella Bruch & Schimp, Physcomitrella patens, Physcomitrella patens (Hedw.) Bruch & Schimp., Physcomitrium patens, Physcomitrium patens (Hedw.) Mitt., bryophytes, mosses
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