Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (317 aa)
Predicted Functional Partners:
Predicted protein (145 aa)
Predicted protein; Belongs to the BI1 family (250 aa)
Adenine phosphoribosyltransferase (286 aa)
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (632 aa)
Predicted protein; Belongs to the adenylate kinase family (356 aa)
Predicted protein; Belongs to the adenylate kinase family (363 aa)
Predicted protein (376 aa)
Predicted protein (378 aa)
Predicted protein; Belongs to the class-I aminoacyl-tRNA synthetase family (692 aa)
Delta-1-pyrroline-5-carboxylate synthase; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family (757 aa)