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PP1S475_4V6.1 protein (Physcomitrella patens) - STRING interaction network
"PP1S475_4V6.1" - DNA topoisomerase in Physcomitrella patens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PP1S475_4V6.1DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (974 aa)    
Predicted Functional Partners:
PP1S15_297V6.1
annotation not available (658 aa)
   
 
  0.986
PP1S243_58V6.1
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily (1315 aa)
   
 
  0.962
PP1S3_646V6.1
annotation not available (1055 aa)
   
 
  0.949
PP1S90_153V6.1
Predicted protein (469 aa)
     
 
  0.946
PP1S9_477V6.1
annotation not available (1376 aa)
   
 
  0.940
PP1S232_56V6.1
Predicted protein (1230 aa)
   
 
  0.923
PP1S222_3V6.1
annotation not available (857 aa)
   
 
  0.923
PP1S152_88V6.1
annotation not available (1174 aa)
   
 
  0.923
PP1S128_34V6.1
annotation not available (871 aa)
   
 
  0.923
PP1S257_1V6.1
Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (479 aa)
     
 
  0.922
Your Current Organism:
Physcomitrella patens
NCBI taxonomy Id: 3218
Other names: P. patens, Physcomitrella patens, Physcomitrella patens (Hedw.) Bruch & Schimp., Physcomitrella patens subsp. patens, Physcomitrium patens, Physcomitrium patens (Hedw.) Mitt.
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