STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPS27Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (732 aa)    
Predicted Functional Partners:
HSE1
Class E vacuolar protein-sorting machinery protein HSE1; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
  
 0.999
STP22
Putative ubiquitin receptor implicated in vacuolar targeting of plasma membrane proteins.
    
 0.997
DID4
Class E vacuolar-protein sorting and endocytosis factor.
    
 0.994
PICST_73878
Uncharacterized protein.
    
 0.993
PICST_82880
AP-1 complex subunit gamma.
    
 0.974
PICST_29338
Uncharacterized protein.
    
  0.969
PICST_58550
Vaculoar sorting protein.
    
 0.936
RSP27
Ubiquitin/40S ribosomal protein S27a fusion.
    
 0.933
PICST_72214
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.909
PICST_59512
Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
    
 0.853
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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