node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO78326.1 | guaA | Avin_21250 | Avin_39720 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.848 |
ACO78326.1 | guaB | Avin_21250 | Avin_39730 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.645 |
ACO78326.1 | purA | Avin_21250 | Avin_07600 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.986 |
ACO78326.1 | purH | Avin_21250 | Avin_06890 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.892 |
ACO78326.1 | purL | Avin_21250 | Avin_39660 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.988 |
argG | asnB | Avin_14080 | Avin_34960 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Asparagine synthase (glutamine-hydrolyzing). | 0.926 |
argG | purA | Avin_14080 | Avin_07600 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.942 |
argG | purL | Avin_14080 | Avin_39660 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.542 |
argG | pyrB | Avin_14080 | Avin_03120 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.910 |
asnB | argG | Avin_34960 | Avin_14080 | Asparagine synthase (glutamine-hydrolyzing). | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.926 |
asnB | guaA | Avin_34960 | Avin_39720 | Asparagine synthase (glutamine-hydrolyzing). | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.524 |
asnB | purA | Avin_34960 | Avin_07600 | Asparagine synthase (glutamine-hydrolyzing). | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.937 |
asnB | purL | Avin_34960 | Avin_39660 | Asparagine synthase (glutamine-hydrolyzing). | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.555 |
asnB | pyrB | Avin_34960 | Avin_03120 | Asparagine synthase (glutamine-hydrolyzing). | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.931 |
guaA | ACO78326.1 | Avin_39720 | Avin_21250 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.848 |
guaA | asnB | Avin_39720 | Avin_34960 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Asparagine synthase (glutamine-hydrolyzing). | 0.524 |
guaA | guaB | Avin_39720 | Avin_39730 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | hpt | Avin_39720 | Avin_41350 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine phosphoribosyltransferase. | 0.953 |
guaA | purA | Avin_39720 | Avin_07600 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.933 |
guaA | purB | Avin_39720 | Avin_28380 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.775 |