node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO76516.1 | ACO77966.1 | Avin_02550 | Avin_17530 | Phosphonate transport system substrate-binding protein. | Phosphonate ABC transporter, periplasmic phosphate-binding protein. | 0.928 |
ACO76516.1 | phnC-3 | Avin_02550 | Avin_19780 | Phosphonate transport system substrate-binding protein. | Phosphonate ABC transporter, ATP binding component; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. | 0.977 |
ACO76516.1 | phnN | Avin_02550 | Avin_07830 | Phosphonate transport system substrate-binding protein. | 1,5 bisphosphokinase (PRPP forming); Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). | 0.601 |
ACO77966.1 | ACO76516.1 | Avin_17530 | Avin_02550 | Phosphonate ABC transporter, periplasmic phosphate-binding protein. | Phosphonate transport system substrate-binding protein. | 0.928 |
ACO77966.1 | phnC-3 | Avin_17530 | Avin_19780 | Phosphonate ABC transporter, periplasmic phosphate-binding protein. | Phosphonate ABC transporter, ATP binding component; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. | 0.975 |
ACO77966.1 | phnN | Avin_17530 | Avin_07830 | Phosphonate ABC transporter, periplasmic phosphate-binding protein. | 1,5 bisphosphokinase (PRPP forming); Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). | 0.658 |
ACO80729.1 | hisG | Avin_46210 | Avin_12920 | Ribose-phosphate pyrophosphokinase. | ATP phosphoribosyltransferase, HIsG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.851 |
ACO80729.1 | hisZ | Avin_46210 | Avin_07590 | Ribose-phosphate pyrophosphokinase. | ATP phosphoribosyl transferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.823 |
ACO80729.1 | phnN | Avin_46210 | Avin_07830 | Ribose-phosphate pyrophosphokinase. | 1,5 bisphosphokinase (PRPP forming); Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). | 0.900 |
ACO80729.1 | prs | Avin_46210 | Avin_41520 | Ribose-phosphate pyrophosphokinase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.924 |
ACO80729.1 | purF | Avin_46210 | Avin_34150 | Ribose-phosphate pyrophosphokinase. | Amidophosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.925 |
ACO80729.1 | pyrE | Avin_46210 | Avin_02880 | Ribose-phosphate pyrophosphokinase. | Orotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.845 |
ACO80816.1 | phnC-3 | Avin_47110 | Avin_19780 | Phosphonate binding protein. | Phosphonate ABC transporter, ATP binding component; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. | 0.886 |
ACO80816.1 | phnN | Avin_47110 | Avin_07830 | Phosphonate binding protein. | 1,5 bisphosphokinase (PRPP forming); Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). | 0.587 |
hisG | ACO80729.1 | Avin_12920 | Avin_46210 | ATP phosphoribosyltransferase, HIsG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | Ribose-phosphate pyrophosphokinase. | 0.851 |
hisG | hisZ | Avin_12920 | Avin_07590 | ATP phosphoribosyltransferase, HIsG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | ATP phosphoribosyl transferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.999 |
hisG | phnN | Avin_12920 | Avin_07830 | ATP phosphoribosyltransferase, HIsG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 1,5 bisphosphokinase (PRPP forming); Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). | 0.800 |
hisG | prs | Avin_12920 | Avin_41520 | ATP phosphoribosyltransferase, HIsG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.851 |
hisG | purF | Avin_12920 | Avin_34150 | ATP phosphoribosyltransferase, HIsG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | Amidophosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.479 |
hisZ | ACO80729.1 | Avin_07590 | Avin_46210 | ATP phosphoribosyl transferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | Ribose-phosphate pyrophosphokinase. | 0.823 |