node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO78736.1 | ACO78738.1 | Avin_25560 | Avin_25580 | Non-ribosomal peptide synthase, PvdD-like protein. | Non-ribosomal peptide synthase, PvdJ(2)-like protein. | 0.999 |
ACO78736.1 | entF | Avin_25560 | Avin_21190 | Non-ribosomal peptide synthase, PvdD-like protein. | Enterochelin sythetase component F (Serine-activating enzyme) (Seryl-AMP ligase). | 0.997 |
ACO78736.1 | hemL | Avin_25560 | Avin_09260 | Non-ribosomal peptide synthase, PvdD-like protein. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.831 |
ACO78738.1 | ACO78736.1 | Avin_25580 | Avin_25560 | Non-ribosomal peptide synthase, PvdJ(2)-like protein. | Non-ribosomal peptide synthase, PvdD-like protein. | 0.999 |
ACO78738.1 | entF | Avin_25580 | Avin_21190 | Non-ribosomal peptide synthase, PvdJ(2)-like protein. | Enterochelin sythetase component F (Serine-activating enzyme) (Seryl-AMP ligase). | 0.997 |
ACO78738.1 | hemL | Avin_25580 | Avin_09260 | Non-ribosomal peptide synthase, PvdJ(2)-like protein. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.687 |
cobA | hemA | Avin_28170 | Avin_41480 | Uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.783 |
cobA | hemB | Avin_28170 | Avin_47450 | Uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.882 |
cobA | hemC | Avin_28170 | Avin_47600 | Uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.988 |
cobA | hemE | Avin_28170 | Avin_45190 | Uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.952 |
cobA | hemL | Avin_28170 | Avin_09260 | Uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.735 |
cobA | nasH | Avin_28170 | Avin_23340 | Uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Uroporphyrin-III C-methyltransferase, NasH. | 0.963 |
entF | ACO78736.1 | Avin_21190 | Avin_25560 | Enterochelin sythetase component F (Serine-activating enzyme) (Seryl-AMP ligase). | Non-ribosomal peptide synthase, PvdD-like protein. | 0.997 |
entF | ACO78738.1 | Avin_21190 | Avin_25580 | Enterochelin sythetase component F (Serine-activating enzyme) (Seryl-AMP ligase). | Non-ribosomal peptide synthase, PvdJ(2)-like protein. | 0.997 |
entF | hemL | Avin_21190 | Avin_09260 | Enterochelin sythetase component F (Serine-activating enzyme) (Seryl-AMP ligase). | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.720 |
hemA | cobA | Avin_41480 | Avin_28170 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.783 |
hemA | hemB | Avin_41480 | Avin_47450 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.879 |
hemA | hemC | Avin_41480 | Avin_47600 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.984 |
hemA | hemE | Avin_41480 | Avin_45190 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.691 |
hemA | hemL | Avin_41480 | Avin_09260 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.997 |