node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nham_0276 | Nham_1816 | Nham_0276 | Nham_1816 | 5-aminolevulinate synthase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.514 |
Nham_0276 | Nham_2814 | Nham_0276 | Nham_2814 | 5-aminolevulinate synthase. | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.744 |
Nham_0276 | Nham_3157 | Nham_0276 | Nham_3157 | 5-aminolevulinate synthase. | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.555 |
Nham_0276 | bioB | Nham_0276 | Nham_0277 | 5-aminolevulinate synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.899 |
Nham_0276 | bioD | Nham_0276 | Nham_2815 | 5-aminolevulinate synthase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.888 |
Nham_1816 | Nham_0276 | Nham_1816 | Nham_0276 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 5-aminolevulinate synthase. | 0.514 |
Nham_1816 | Nham_2206 | Nham_1816 | Nham_2206 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Biotin--acetyl-CoA-carboxylase ligase. | 0.540 |
Nham_1816 | Nham_2814 | Nham_1816 | Nham_2814 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.431 |
Nham_1816 | Nham_2816 | Nham_1816 | Nham_2816 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 8-amino-7-oxononanoate synthase. | 0.514 |
Nham_1816 | Nham_3157 | Nham_1816 | Nham_3157 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.431 |
Nham_1816 | bioB | Nham_1816 | Nham_0277 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.446 |
Nham_1816 | bioD | Nham_1816 | Nham_2815 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.452 |
Nham_1816 | nadA | Nham_1816 | Nham_2819 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.547 |
Nham_1816 | thiC | Nham_1816 | Nham_2896 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.414 |
Nham_2206 | Nham_1816 | Nham_2206 | Nham_1816 | Biotin--acetyl-CoA-carboxylase ligase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.540 |
Nham_2206 | bioB | Nham_2206 | Nham_0277 | Biotin--acetyl-CoA-carboxylase ligase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.937 |
Nham_2206 | bioD | Nham_2206 | Nham_2815 | Biotin--acetyl-CoA-carboxylase ligase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.412 |
Nham_2814 | Nham_0276 | Nham_2814 | Nham_0276 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 5-aminolevulinate synthase. | 0.744 |
Nham_2814 | Nham_1816 | Nham_2814 | Nham_1816 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.431 |
Nham_2814 | Nham_2816 | Nham_2814 | Nham_2816 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase. | 0.997 |