node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nham_0113 | aroE | Nham_0113 | Nham_1109 | Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.656 |
Nham_0984 | Nham_1044 | Nham_0984 | Nham_1044 | 3-dehydroquinate synthase. | Anthranilate synthase, component II / anthranilate synthase, component I. | 0.624 |
Nham_0984 | Nham_3238 | Nham_0984 | Nham_3238 | 3-dehydroquinate synthase. | Anthranilate synthase, component I. | 0.624 |
Nham_0984 | aroA | Nham_0984 | Nham_0165 | 3-dehydroquinate synthase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.712 |
Nham_0984 | aroB | Nham_0984 | Nham_0491 | 3-dehydroquinate synthase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.923 |
Nham_0984 | aroC | Nham_0984 | Nham_0770 | 3-dehydroquinate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.898 |
Nham_0984 | aroE | Nham_0984 | Nham_1109 | 3-dehydroquinate synthase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.813 |
Nham_0984 | aroK | Nham_0984 | Nham_0490 | 3-dehydroquinate synthase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.978 |
Nham_0984 | aroQ | Nham_0984 | Nham_2187 | 3-dehydroquinate synthase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.936 |
Nham_1044 | Nham_0984 | Nham_1044 | Nham_0984 | Anthranilate synthase, component II / anthranilate synthase, component I. | 3-dehydroquinate synthase. | 0.624 |
Nham_1044 | Nham_3238 | Nham_1044 | Nham_3238 | Anthranilate synthase, component II / anthranilate synthase, component I. | Anthranilate synthase, component I. | 0.999 |
Nham_1044 | aroA | Nham_1044 | Nham_0165 | Anthranilate synthase, component II / anthranilate synthase, component I. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.579 |
Nham_1044 | aroB | Nham_1044 | Nham_0491 | Anthranilate synthase, component II / anthranilate synthase, component I. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.724 |
Nham_1044 | aroC | Nham_1044 | Nham_0770 | Anthranilate synthase, component II / anthranilate synthase, component I. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.954 |
Nham_1044 | aroE | Nham_1044 | Nham_1109 | Anthranilate synthase, component II / anthranilate synthase, component I. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.753 |
Nham_1044 | aroK | Nham_1044 | Nham_0490 | Anthranilate synthase, component II / anthranilate synthase, component I. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.634 |
Nham_1044 | aroQ | Nham_1044 | Nham_2187 | Anthranilate synthase, component II / anthranilate synthase, component I. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.513 |
Nham_3238 | Nham_0984 | Nham_3238 | Nham_0984 | Anthranilate synthase, component I. | 3-dehydroquinate synthase. | 0.624 |
Nham_3238 | Nham_1044 | Nham_3238 | Nham_1044 | Anthranilate synthase, component I. | Anthranilate synthase, component II / anthranilate synthase, component I. | 0.999 |
Nham_3238 | aroA | Nham_3238 | Nham_0165 | Anthranilate synthase, component I. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.518 |