node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nham_0553 | ligA | Nham_0553 | Nham_1290 | ATP dependent DNA ligase. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.908 |
Nham_0553 | polA | Nham_0553 | Nham_0453 | ATP dependent DNA ligase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.843 |
Nham_1289 | ligA | Nham_1289 | Nham_1290 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.877 |
Nham_1289 | pheT | Nham_1289 | Nham_0073 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.682 |
Nham_1289 | polA | Nham_1289 | Nham_0453 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.506 |
Nham_1289 | topA | Nham_1289 | Nham_2437 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.489 |
Nham_1995 | ligA | Nham_1995 | Nham_1290 | Superfamily I DNA and RNA helicases-like protein. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.611 |
Nham_1995 | polA | Nham_1995 | Nham_0453 | Superfamily I DNA and RNA helicases-like protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.630 |
Nham_1995 | topA | Nham_1995 | Nham_2437 | Superfamily I DNA and RNA helicases-like protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.576 |
Nham_2739 | Nham_3768 | Nham_2739 | Nham_3768 | ATP-dependent DNA helicase, Rep family. | ATP-dependent DNA helicase, Rep family. | 0.907 |
Nham_2739 | ligA | Nham_2739 | Nham_1290 | ATP-dependent DNA helicase, Rep family. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.721 |
Nham_2739 | pheT | Nham_2739 | Nham_0073 | ATP-dependent DNA helicase, Rep family. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.578 |
Nham_2739 | polA | Nham_2739 | Nham_0453 | ATP-dependent DNA helicase, Rep family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.676 |
Nham_2739 | topA | Nham_2739 | Nham_2437 | ATP-dependent DNA helicase, Rep family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.644 |
Nham_3768 | Nham_2739 | Nham_3768 | Nham_2739 | ATP-dependent DNA helicase, Rep family. | ATP-dependent DNA helicase, Rep family. | 0.907 |
Nham_3768 | ligA | Nham_3768 | Nham_1290 | ATP-dependent DNA helicase, Rep family. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.681 |
Nham_3768 | polA | Nham_3768 | Nham_0453 | ATP-dependent DNA helicase, Rep family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.630 |
Nham_3768 | topA | Nham_3768 | Nham_2437 | ATP-dependent DNA helicase, Rep family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.576 |
leuS | ligA | Nham_0098 | Nham_1290 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.845 |
leuS | pheS | Nham_0098 | Nham_0074 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.579 |