node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nham_0276 | Nham_1620 | Nham_0276 | Nham_1620 | 5-aminolevulinate synthase. | Glycine cleavage system T protein. | 0.476 |
Nham_0276 | Nham_2804 | Nham_0276 | Nham_2804 | 5-aminolevulinate synthase. | Serine--glyoxylate transaminase. | 0.911 |
Nham_0276 | gcvP | Nham_0276 | Nham_1618 | 5-aminolevulinate synthase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.945 |
Nham_0276 | glyA | Nham_0276 | Nham_1814 | 5-aminolevulinate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
Nham_0537 | Nham_1620 | Nham_0537 | Nham_1620 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein. | 0.967 |
Nham_0537 | Nham_1752 | Nham_0537 | Nham_1752 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.912 |
Nham_0537 | Nham_2804 | Nham_0537 | Nham_2804 | Dihydrolipoamide dehydrogenase. | Serine--glyoxylate transaminase. | 0.904 |
Nham_0537 | Nham_3618 | Nham_0537 | Nham_3618 | Dihydrolipoamide dehydrogenase. | Succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.527 |
Nham_0537 | gcvH | Nham_0537 | Nham_1619 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.983 |
Nham_0537 | gcvP | Nham_0537 | Nham_1618 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.959 |
Nham_0537 | glyA | Nham_0537 | Nham_1814 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.922 |
Nham_0537 | purQ | Nham_0537 | Nham_1635 | Dihydrolipoamide dehydrogenase. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.803 |
Nham_1620 | Nham_0276 | Nham_1620 | Nham_0276 | Glycine cleavage system T protein. | 5-aminolevulinate synthase. | 0.476 |
Nham_1620 | Nham_0537 | Nham_1620 | Nham_0537 | Glycine cleavage system T protein. | Dihydrolipoamide dehydrogenase. | 0.967 |
Nham_1620 | Nham_1752 | Nham_1620 | Nham_1752 | Glycine cleavage system T protein. | Dihydrolipoamide dehydrogenase. | 0.964 |
Nham_1620 | Nham_2804 | Nham_1620 | Nham_2804 | Glycine cleavage system T protein. | Serine--glyoxylate transaminase. | 0.941 |
Nham_1620 | gcvH | Nham_1620 | Nham_1619 | Glycine cleavage system T protein. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
Nham_1620 | gcvP | Nham_1620 | Nham_1618 | Glycine cleavage system T protein. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
Nham_1620 | glyA | Nham_1620 | Nham_1814 | Glycine cleavage system T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
Nham_1620 | purD | Nham_1620 | Nham_3173 | Glycine cleavage system T protein. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.462 |