node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nham_0002 | Nham_0448 | Nham_0002 | Nham_0448 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase LigD polymerase module. | 0.893 |
Nham_0002 | Nham_3852 | Nham_0002 | Nham_3852 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP dependent DNA ligase. | 0.889 |
Nham_0002 | Nham_3905 | Nham_0002 | Nham_3905 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP dependent DNA ligase. | 0.889 |
Nham_0002 | Nham_3907 | Nham_0002 | Nham_3907 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase LigD polymerase module. | 0.893 |
Nham_0002 | polA | Nham_0002 | Nham_0453 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
Nham_0448 | Nham_0002 | Nham_0448 | Nham_0002 | ATP-dependent DNA ligase LigD polymerase module. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.893 |
Nham_0448 | Nham_3852 | Nham_0448 | Nham_3852 | ATP-dependent DNA ligase LigD polymerase module. | ATP dependent DNA ligase. | 0.919 |
Nham_0448 | Nham_3905 | Nham_0448 | Nham_3905 | ATP-dependent DNA ligase LigD polymerase module. | ATP dependent DNA ligase. | 0.415 |
Nham_0448 | Nham_3907 | Nham_0448 | Nham_3907 | ATP-dependent DNA ligase LigD polymerase module. | ATP-dependent DNA ligase LigD polymerase module. | 0.935 |
Nham_0448 | Nham_3998 | Nham_0448 | Nham_3998 | ATP-dependent DNA ligase LigD polymerase module. | Putative DNA topoisomerase I. | 0.712 |
Nham_0448 | ku | Nham_0448 | Nham_0450 | ATP-dependent DNA ligase LigD polymerase module. | Conserved hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.965 |
Nham_0448 | ku-2 | Nham_0448 | Nham_3871 | ATP-dependent DNA ligase LigD polymerase module. | Conserved hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.909 |
Nham_0448 | ku-3 | Nham_0448 | Nham_3906 | ATP-dependent DNA ligase LigD polymerase module. | Conserved hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.909 |
Nham_0448 | ku-4 | Nham_0448 | Nham_3917 | ATP-dependent DNA ligase LigD polymerase module. | Conserved hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.909 |
Nham_0448 | polA | Nham_0448 | Nham_0453 | ATP-dependent DNA ligase LigD polymerase module. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.907 |
Nham_3852 | Nham_0002 | Nham_3852 | Nham_0002 | ATP dependent DNA ligase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.889 |
Nham_3852 | Nham_0448 | Nham_3852 | Nham_0448 | ATP dependent DNA ligase. | ATP-dependent DNA ligase LigD polymerase module. | 0.919 |
Nham_3852 | Nham_3907 | Nham_3852 | Nham_3907 | ATP dependent DNA ligase. | ATP-dependent DNA ligase LigD polymerase module. | 0.918 |
Nham_3852 | Nham_3998 | Nham_3852 | Nham_3998 | ATP dependent DNA ligase. | Putative DNA topoisomerase I. | 0.660 |
Nham_3852 | ku | Nham_3852 | Nham_0450 | ATP dependent DNA ligase. | Conserved hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.806 |