node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nwi_0002 | Nwi_0462 | Nwi_0002 | Nwi_0462 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP dependent DNA ligase. | 0.952 |
Nwi_0002 | Nwi_0907 | Nwi_0002 | Nwi_0907 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Conserved hypothetical protein. | 0.567 |
Nwi_0002 | Nwi_0908 | Nwi_0002 | Nwi_0908 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease SbcD. | 0.561 |
Nwi_0002 | Nwi_1919 | Nwi_0002 | Nwi_1919 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Signal peptidase I, Serine peptidase, MEROPS family S26A; Belongs to the peptidase S26 family. | 0.425 |
Nwi_0002 | ligA | Nwi_0002 | Nwi_1062 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.476 |
Nwi_0002 | polA | Nwi_0002 | Nwi_0357 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
Nwi_0186 | Nwi_0187 | Nwi_0186 | Nwi_0187 | Metallophosphoesterase. | ATP dependent helicase, Lhr family. | 0.957 |
Nwi_0186 | Nwi_0461 | Nwi_0186 | Nwi_0461 | Metallophosphoesterase. | Conserved hypothetical protein. | 0.798 |
Nwi_0186 | Nwi_0462 | Nwi_0186 | Nwi_0462 | Metallophosphoesterase. | ATP dependent DNA ligase. | 0.820 |
Nwi_0187 | Nwi_0186 | Nwi_0187 | Nwi_0186 | ATP dependent helicase, Lhr family. | Metallophosphoesterase. | 0.957 |
Nwi_0187 | Nwi_0461 | Nwi_0187 | Nwi_0461 | ATP dependent helicase, Lhr family. | Conserved hypothetical protein. | 0.803 |
Nwi_0187 | Nwi_0462 | Nwi_0187 | Nwi_0462 | ATP dependent helicase, Lhr family. | ATP dependent DNA ligase. | 0.802 |
Nwi_0461 | Nwi_0186 | Nwi_0461 | Nwi_0186 | Conserved hypothetical protein. | Metallophosphoesterase. | 0.798 |
Nwi_0461 | Nwi_0187 | Nwi_0461 | Nwi_0187 | Conserved hypothetical protein. | ATP dependent helicase, Lhr family. | 0.803 |
Nwi_0461 | Nwi_0462 | Nwi_0461 | Nwi_0462 | Conserved hypothetical protein. | ATP dependent DNA ligase. | 0.985 |
Nwi_0461 | Nwi_0907 | Nwi_0461 | Nwi_0907 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.627 |
Nwi_0461 | Nwi_0908 | Nwi_0461 | Nwi_0908 | Conserved hypothetical protein. | Exonuclease SbcD. | 0.685 |
Nwi_0461 | polA | Nwi_0461 | Nwi_0357 | Conserved hypothetical protein. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.816 |
Nwi_0462 | Nwi_0002 | Nwi_0462 | Nwi_0002 | ATP dependent DNA ligase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.952 |
Nwi_0462 | Nwi_0186 | Nwi_0462 | Nwi_0186 | ATP dependent DNA ligase. | Metallophosphoesterase. | 0.820 |