node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nwi_0103 | aroE | Nwi_0103 | Nwi_2977 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.646 |
Nwi_0951 | Nwi_2614 | Nwi_0951 | Nwi_2614 | Anthranilate synthase, component II. | Anthranilate synthase, component I / anthranilate synthase, component II. | 0.999 |
Nwi_0951 | aroA | Nwi_0951 | Nwi_0209 | Anthranilate synthase, component II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.596 |
Nwi_0951 | aroB | Nwi_0951 | Nwi_0396 | Anthranilate synthase, component II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.696 |
Nwi_0951 | aroC | Nwi_0951 | Nwi_0629 | Anthranilate synthase, component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.953 |
Nwi_0951 | aroE | Nwi_0951 | Nwi_2977 | Anthranilate synthase, component II. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.743 |
Nwi_0951 | aroK | Nwi_0951 | Nwi_0395 | Anthranilate synthase, component II. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.682 |
Nwi_0951 | aroQ | Nwi_0951 | Nwi_1751 | Anthranilate synthase, component II. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.522 |
Nwi_2298 | Nwi_2614 | Nwi_2298 | Nwi_2614 | Xylose isomerase-like TIM barrel. | Anthranilate synthase, component I / anthranilate synthase, component II. | 0.836 |
Nwi_2298 | aroC | Nwi_2298 | Nwi_0629 | Xylose isomerase-like TIM barrel. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.800 |
Nwi_2298 | aroE | Nwi_2298 | Nwi_2977 | Xylose isomerase-like TIM barrel. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.830 |
Nwi_2298 | aroQ | Nwi_2298 | Nwi_1751 | Xylose isomerase-like TIM barrel. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.831 |
Nwi_2614 | Nwi_0951 | Nwi_2614 | Nwi_0951 | Anthranilate synthase, component I / anthranilate synthase, component II. | Anthranilate synthase, component II. | 0.999 |
Nwi_2614 | Nwi_2298 | Nwi_2614 | Nwi_2298 | Anthranilate synthase, component I / anthranilate synthase, component II. | Xylose isomerase-like TIM barrel. | 0.836 |
Nwi_2614 | aroA | Nwi_2614 | Nwi_0209 | Anthranilate synthase, component I / anthranilate synthase, component II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.534 |
Nwi_2614 | aroB | Nwi_2614 | Nwi_0396 | Anthranilate synthase, component I / anthranilate synthase, component II. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.634 |
Nwi_2614 | aroC | Nwi_2614 | Nwi_0629 | Anthranilate synthase, component I / anthranilate synthase, component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.967 |
Nwi_2614 | aroE | Nwi_2614 | Nwi_2977 | Anthranilate synthase, component I / anthranilate synthase, component II. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.693 |
Nwi_2614 | aroK | Nwi_2614 | Nwi_0395 | Anthranilate synthase, component I / anthranilate synthase, component II. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.610 |
Nwi_2614 | aroQ | Nwi_2614 | Nwi_1751 | Anthranilate synthase, component I / anthranilate synthase, component II. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.522 |