STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmBProteasome endopeptidase complex, beta component, Threonine peptidase, MEROPS family T01A; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (209 aa)    
Predicted Functional Partners:
psmA
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.999
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
 
 0.988
Mhun_2403
Proteasome Rpn11 subunit JAMM motif, Metallo peptidase, MEROPS family M67B.
   
 0.987
Mhun_1040
Proteasome-activating nucleotidase; Belongs to the AAA ATPase family.
  
 0.986
rpl40e
LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.966
Mhun_0845
Beta-lactamase-like protein.
 
   
 0.885
Mhun_2224
Serine/threonine protein kinase.
   
 0.820
Mhun_0058
Conserved hypothetical protein.
 
 
 
 0.753
Mhun_2338
AAA ATPase, central region; Belongs to the AAA ATPase family.
  
 0.750
Mhun_0817
AAA family ATPase, CDC48 subfamily.
  
 0.746
Your Current Organism:
Methanospirillum hungatei
NCBI taxonomy Id: 323259
Other names: M. hungatei JF-1, Methanospirillum hungatei DSM 864, Methanospirillum hungatei JF-1, Methanospirillum hungatei NBRC 100397, Methanospirillum hungatei str. JF-1, Methanospirillum hungatei strain JF-1
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