STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (269 aa)    
Predicted Functional Partners:
Mhun_0903
D-fructose 1,6-bisphosphatase.
 
  
 0.987
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
  
 0.961
Mhun_2915
Nicotinamide-nucleotide adenylyltransferase.
    
 0.932
Mhun_1582
NUDIX hydrolase.
     
 0.915
srp54
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
    0.762
Mhun_0901
Protein of unknown function DUF169.
 
     0.679
eif5a
Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
       0.660
Mhun_2593
Nicotinate phosphoribosyltransferase related protein.
 
   
 0.624
Mhun_0900
TPR repeat.
 
   
 0.580
Mhun_2886
Geranylgeranyl-diphosphate synthase / farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 
 0.544
Your Current Organism:
Methanospirillum hungatei
NCBI taxonomy Id: 323259
Other names: M. hungatei JF-1, Methanospirillum hungatei DSM 864, Methanospirillum hungatei JF-1, Methanospirillum hungatei NBRC 100397, Methanospirillum hungatei str. JF-1, Methanospirillum hungatei strain JF-1
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