STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mhun_2411Peptidase S26B, signal peptidase. (235 aa)    
Predicted Functional Partners:
atpE1
H+-transporting two-sector ATPase, E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
 0.923
lig
DNA ligase I, ATP-dependent (dnl1); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
    
 0.923
Mhun_0346
Peptidase S9B, dipeptidylpeptidase IV-like protein.
  
 
 0.878
Mhun_1301
Peptidase S9, prolyl oligopeptidase active site region.
  
 
 0.878
atpF
Vacuolar H+-transporting two-sector ATPase, F subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
  0.873
atpC-3
H+-transporting two-sector ATPase, C (AC39) subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
 0.861
atpC
H+-transporting two-sector ATPase, C (AC39) subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
 0.856
Mhun_2410
FO synthase subunit 2.
       0.845
rnhB
RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.839
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
  
 0.822
Your Current Organism:
Methanospirillum hungatei
NCBI taxonomy Id: 323259
Other names: M. hungatei JF-1, Methanospirillum hungatei DSM 864, Methanospirillum hungatei JF-1, Methanospirillum hungatei NBRC 100397, Methanospirillum hungatei str. JF-1, Methanospirillum hungatei strain JF-1
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