STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mhun_2868O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase fami [...] (520 aa)    
Predicted Functional Partners:
Mhun_2467
Hypothetical protein.
    
 
 0.999
rps24e
SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
 
    0.979
Mhun_0562
Translation factor SUA5.
 
 
 0.946
Mhun_2869
dITPase; Belongs to the HAM1 NTPase family.
 
   
 0.937
Mhun_2861
Translation initiation factor 2 subunit gamma (aeIF-2g).
 
   
 0.931
infB
Translation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
  
 0.920
rps27ae
SSU ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.919
Mhun_2862
SSU processome protein Utp24.
 
     0.902
Mhun_2863
DNA-directed RNA polymerase, subunit E'.
 
     0.901
Mhun_2865
Protein of unknown function DUF359; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
     0.896
Your Current Organism:
Methanospirillum hungatei
NCBI taxonomy Id: 323259
Other names: M. hungatei JF-1, Methanospirillum hungatei DSM 864, Methanospirillum hungatei JF-1, Methanospirillum hungatei NBRC 100397, Methanospirillum hungatei str. JF-1, Methanospirillum hungatei strain JF-1
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