node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Noc_1388 | Noc_2425 | Noc_1388 | Noc_2425 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | 0.804 |
Noc_1388 | clpB | Noc_1388 | Noc_2381 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.827 |
Noc_1388 | dnaK | Noc_1388 | Noc_2811 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.410 |
Noc_1388 | grpE | Noc_1388 | Noc_2812 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.484 |
Noc_1388 | hslV | Noc_1388 | Noc_2340 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | HslV component of HslUV peptidase, Threonine peptidase, MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.460 |
Noc_1388 | htpG | Noc_1388 | Noc_1718 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.600 |
Noc_1388 | lon | Noc_1388 | Noc_1387 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Peptidase S16, ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.829 |
Noc_2425 | Noc_1388 | Noc_2425 | Noc_1388 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | 0.804 |
Noc_2425 | dnaJ | Noc_2425 | Noc_2810 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.843 |
Noc_2425 | dnaK | Noc_2425 | Noc_2811 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.961 |
Noc_2425 | groL | Noc_2425 | Noc_2921 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.777 |
Noc_2425 | grpE | Noc_2425 | Noc_2812 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.879 |
Noc_2425 | hslU | Noc_2425 | Noc_2341 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Heat shock protein HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.731 |
Noc_2425 | hslV | Noc_2425 | Noc_2340 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | HslV component of HslUV peptidase, Threonine peptidase, MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.487 |
Noc_2425 | htpG | Noc_2425 | Noc_1718 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.844 |
Noc_2425 | lon | Noc_2425 | Noc_1387 | ATP-dependent Clp protease; Belongs to the ClpA/ClpB family. | Peptidase S16, ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.751 |
clpB | Noc_1388 | Noc_2381 | Noc_1388 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | 0.827 |
clpB | dnaJ | Noc_2381 | Noc_2810 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.843 |
clpB | dnaK | Noc_2381 | Noc_2811 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.961 |
clpB | groL | Noc_2381 | Noc_2921 | ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperonin Cpn60/TCP-1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.777 |