node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABB73530.1 | metXS | Nmul_A0222 | Nmul_A0221 | Methionine biosynthesis MetW. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.998 |
ABB73648.1 | ABB73778.1 | Nmul_A0340 | Nmul_A0470 | L-serine ammonia-lyase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
ABB73648.1 | ABB73943.1 | Nmul_A0340 | Nmul_A0636 | L-serine ammonia-lyase. | Phosphoserine phosphatase. | 0.909 |
ABB73648.1 | ABB74800.1 | Nmul_A0340 | Nmul_A1497 | L-serine ammonia-lyase. | O-acetylhomoserine sulfhydrolase. | 0.807 |
ABB73648.1 | ABB74854.1 | Nmul_A0340 | Nmul_A1551 | L-serine ammonia-lyase. | Homoserine dehydrogenase. | 0.879 |
ABB73648.1 | glyA | Nmul_A0340 | Nmul_A0004 | L-serine ammonia-lyase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.913 |
ABB73648.1 | ilvA | Nmul_A0340 | Nmul_A0437 | L-serine ammonia-lyase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.923 |
ABB73648.1 | metXS | Nmul_A0340 | Nmul_A0221 | L-serine ammonia-lyase. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.831 |
ABB73648.1 | metZ | Nmul_A0340 | Nmul_A1905 | L-serine ammonia-lyase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.842 |
ABB73778.1 | ABB73648.1 | Nmul_A0470 | Nmul_A0340 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-serine ammonia-lyase. | 0.900 |
ABB73778.1 | ABB73943.1 | Nmul_A0470 | Nmul_A0636 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphoserine phosphatase. | 0.904 |
ABB73778.1 | glyA | Nmul_A0470 | Nmul_A0004 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
ABB73778.1 | ilvA | Nmul_A0470 | Nmul_A0437 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.900 |
ABB73778.1 | metXS | Nmul_A0470 | Nmul_A0221 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.800 |
ABB73943.1 | ABB73648.1 | Nmul_A0636 | Nmul_A0340 | Phosphoserine phosphatase. | L-serine ammonia-lyase. | 0.909 |
ABB73943.1 | ABB73778.1 | Nmul_A0636 | Nmul_A0470 | Phosphoserine phosphatase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.904 |
ABB73943.1 | glyA | Nmul_A0636 | Nmul_A0004 | Phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
ABB73943.1 | ilvA | Nmul_A0636 | Nmul_A0437 | Phosphoserine phosphatase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.909 |
ABB73943.1 | metXS | Nmul_A0636 | Nmul_A0221 | Phosphoserine phosphatase. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.803 |
ABB74800.1 | ABB73648.1 | Nmul_A1497 | Nmul_A0340 | O-acetylhomoserine sulfhydrolase. | L-serine ammonia-lyase. | 0.807 |