node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABB74449.1 | ABB74450.1 | Nmul_A1146 | Nmul_A1147 | Nitrite and sulphite reductase 4Fe-4S region; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | 0.999 |
ABB74449.1 | ABB74451.1 | Nmul_A1146 | Nmul_A1148 | Nitrite and sulphite reductase 4Fe-4S region; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Sulfate adenylyltransferase subunit 2. | 0.977 |
ABB74449.1 | cysC | Nmul_A1146 | Nmul_A0299 | Nitrite and sulphite reductase 4Fe-4S region; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.938 |
ABB74449.1 | cysG | Nmul_A1146 | Nmul_A2313 | Nitrite and sulphite reductase 4Fe-4S region; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Precorrin-2 dehydrogenase / uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.992 |
ABB74449.1 | hemC | Nmul_A1146 | Nmul_A2690 | Nitrite and sulphite reductase 4Fe-4S region; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.433 |
ABB74450.1 | ABB74449.1 | Nmul_A1147 | Nmul_A1146 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Nitrite and sulphite reductase 4Fe-4S region; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.999 |
ABB74450.1 | ABB74451.1 | Nmul_A1147 | Nmul_A1148 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Sulfate adenylyltransferase subunit 2. | 0.999 |
ABB74450.1 | cysC | Nmul_A1147 | Nmul_A0299 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.999 |
ABB74450.1 | cysG | Nmul_A1147 | Nmul_A2313 | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | Precorrin-2 dehydrogenase / uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.972 |
ABB74451.1 | ABB74449.1 | Nmul_A1148 | Nmul_A1146 | Sulfate adenylyltransferase subunit 2. | Nitrite and sulphite reductase 4Fe-4S region; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.977 |
ABB74451.1 | ABB74450.1 | Nmul_A1148 | Nmul_A1147 | Sulfate adenylyltransferase subunit 2. | Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. | 0.999 |
ABB74451.1 | cysC | Nmul_A1148 | Nmul_A0299 | Sulfate adenylyltransferase subunit 2. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.998 |
ABB74451.1 | cysG | Nmul_A1148 | Nmul_A2313 | Sulfate adenylyltransferase subunit 2. | Precorrin-2 dehydrogenase / uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.953 |
ABB75373.1 | ABB75976.1 | Nmul_A2079 | Nmul_A2689 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.944 |
ABB75373.1 | cysG | Nmul_A2079 | Nmul_A2313 | Porphobilinogen synthase; Belongs to the ALAD family. | Precorrin-2 dehydrogenase / uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.936 |
ABB75373.1 | hemA | Nmul_A2079 | Nmul_A2642 | Porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.878 |
ABB75373.1 | hemC | Nmul_A2079 | Nmul_A2690 | Porphobilinogen synthase; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
ABB75373.1 | hemE | Nmul_A2079 | Nmul_A0705 | Porphobilinogen synthase; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.789 |
ABB75975.1 | ABB75976.1 | Nmul_A2688 | Nmul_A2689 | Protein of unknown function DUF513. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.997 |
ABB75975.1 | cysG | Nmul_A2688 | Nmul_A2313 | Protein of unknown function DUF513. | Precorrin-2 dehydrogenase / uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.914 |