STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fadA3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa)    
Predicted Functional Partners:
fadB
3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 0.999
fadJ
3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 0.999
Shew_2864
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: pat:Patl_1916 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.999
Shew_2108
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: shm:Shewmr7_2223 acyl-CoA dehydrogenase domain protein.
 
 0.958
Shew_2051
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: son:SO2492 oxidoreductase, acyl-CoA dehydrogenase family.
 
 0.952
Shew_3003
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAb0374 acyl-coenzyme A dehydrogenase (ACDH).
 
 0.951
Shew_0900
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sdn:Sden_3018 acyl-CoA dehydrogenase-like protein.
  
 0.943
Shew_2860
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sfr:Sfri_2069 acyl-CoA dehydrogenase domain protein.
  
 0.943
Shew_2574
hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase; KEGG: sfr:Sfri_2731 pyruvate carboxyltransferase.
  
 
 0.928
fadI
3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
  
 
0.921
Your Current Organism:
Shewanella loihica
NCBI taxonomy Id: 323850
Other names: S. loihica PV-4, Shewanella loihica PV-4, Shewanella loihica str. PV-4, Shewanella loihica strain PV-4, Shewanella sp. PV-4
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