node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Shew_0687 | Shew_1566 | Shew_0687 | Shew_1566 | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.665 |
Shew_0687 | Shew_2431 | Shew_0687 | Shew_2431 | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | PFAM: TPR repeat-containing protein; von Willebrand factor, type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_1467 tetratricopeptide TPR_2 repeat protein. | 0.604 |
Shew_0687 | clpB | Shew_0687 | Shew_2948 | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.665 |
Shew_0687 | dnaK | Shew_0687 | Shew_2844 | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.868 |
Shew_0687 | groL | Shew_0687 | Shew_0472 | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.740 |
Shew_0687 | groS | Shew_0687 | Shew_0471 | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.615 |
Shew_0687 | grpE | Shew_0687 | Shew_2772 | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.854 |
Shew_0687 | htpG | Shew_0687 | Shew_2232 | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.904 |
Shew_1566 | Shew_0687 | Shew_1566 | Shew_0687 | KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | 0.665 |
Shew_1566 | dnaJ | Shew_1566 | Shew_2843 | KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.679 |
Shew_1566 | dnaK | Shew_1566 | Shew_2844 | KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.910 |
Shew_1566 | groL | Shew_1566 | Shew_0472 | KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.595 |
Shew_1566 | groS | Shew_1566 | Shew_0471 | KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.627 |
Shew_1566 | grpE | Shew_1566 | Shew_2772 | KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.794 |
Shew_1566 | htpG | Shew_1566 | Shew_2232 | KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.698 |
Shew_2316 | dnaJ | Shew_2316 | Shew_2843 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.403 |
Shew_2316 | dnaK | Shew_2316 | Shew_2844 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.902 |
Shew_2431 | Shew_0687 | Shew_2431 | Shew_0687 | PFAM: TPR repeat-containing protein; von Willebrand factor, type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_1467 tetratricopeptide TPR_2 repeat protein. | PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein. | 0.604 |
Shew_2431 | dnaJ | Shew_2431 | Shew_2843 | PFAM: TPR repeat-containing protein; von Willebrand factor, type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_1467 tetratricopeptide TPR_2 repeat protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.604 |
Shew_2431 | dnaK | Shew_2431 | Shew_2844 | PFAM: TPR repeat-containing protein; von Willebrand factor, type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_1467 tetratricopeptide TPR_2 repeat protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.883 |