node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Shew_1452 | Shew_1453 | Shew_1452 | Shew_1453 | DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine--protein-cysteine S-methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: she:Shewmr4_1367 transcriptional regulator, AraC family. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.925 |
Shew_1452 | Shew_2885 | Shew_1452 | Shew_2885 | DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine--protein-cysteine S-methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: she:Shewmr4_1367 transcriptional regulator, AraC family. | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | 0.539 |
Shew_1453 | Shew_1452 | Shew_1453 | Shew_1452 | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine--protein-cysteine S-methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: she:Shewmr4_1367 transcriptional regulator, AraC family. | 0.925 |
Shew_1453 | Shew_2885 | Shew_1453 | Shew_2885 | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | 0.408 |
Shew_2883 | Shew_2884 | Shew_2883 | Shew_2884 | Transcriptional regulator BolA; PFAM: BolA family protein; KEGG: she:Shewmr4_0932 BolA family protein; Belongs to the BolA/IbaG family. | KEGG: sfr:Sfri_3629 glycine cleavage system regulatory protein-like protein. | 0.498 |
Shew_2883 | Shew_2885 | Shew_2883 | Shew_2885 | Transcriptional regulator BolA; PFAM: BolA family protein; KEGG: she:Shewmr4_0932 BolA family protein; Belongs to the BolA/IbaG family. | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | 0.427 |
Shew_2884 | Shew_2883 | Shew_2884 | Shew_2883 | KEGG: sfr:Sfri_3629 glycine cleavage system regulatory protein-like protein. | Transcriptional regulator BolA; PFAM: BolA family protein; KEGG: she:Shewmr4_0932 BolA family protein; Belongs to the BolA/IbaG family. | 0.498 |
Shew_2884 | Shew_2885 | Shew_2884 | Shew_2885 | KEGG: sfr:Sfri_3629 glycine cleavage system regulatory protein-like protein. | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | 0.495 |
Shew_2885 | Shew_1452 | Shew_2885 | Shew_1452 | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine--protein-cysteine S-methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: she:Shewmr4_1367 transcriptional regulator, AraC family. | 0.539 |
Shew_2885 | Shew_1453 | Shew_2885 | Shew_1453 | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.408 |
Shew_2885 | Shew_2883 | Shew_2885 | Shew_2883 | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | Transcriptional regulator BolA; PFAM: BolA family protein; KEGG: she:Shewmr4_0932 BolA family protein; Belongs to the BolA/IbaG family. | 0.427 |
Shew_2885 | Shew_2884 | Shew_2885 | Shew_2884 | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | KEGG: sfr:Sfri_3629 glycine cleavage system regulatory protein-like protein. | 0.495 |
Shew_2885 | Shew_2895 | Shew_2885 | Shew_2895 | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.660 |
Shew_2885 | rlmG | Shew_2885 | Shew_2886 | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.590 |
Shew_2895 | Shew_2885 | Shew_2895 | Shew_2885 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | 0.660 |
rlmG | Shew_2885 | Shew_2886 | Shew_2885 | rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | DNA-N1-methyladenine dioxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase. | 0.590 |