node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Shew_0901 | Shew_1656 | Shew_0901 | Shew_1656 | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.999 |
Shew_0901 | Shew_1927 | Shew_0901 | Shew_1927 | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes. | 0.999 |
Shew_0901 | Shew_3429 | Shew_0901 | Shew_3429 | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shm:Shewmr7_3597 dihydrolipoamide dehydrogenase. | 0.999 |
Shew_0901 | Shew_3430 | Shew_0901 | Shew_3430 | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
Shew_0901 | gcvH | Shew_0901 | Shew_3063 | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.824 |
Shew_0901 | gcvP | Shew_0901 | Shew_3062 | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.433 |
Shew_0901 | lipA | Shew_0901 | Shew_2942 | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.548 |
Shew_0901 | lipB | Shew_0901 | Shew_2941 | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.547 |
Shew_1656 | Shew_0901 | Shew_1656 | Shew_0901 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | 0.999 |
Shew_1656 | Shew_3429 | Shew_1656 | Shew_3429 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shm:Shewmr7_3597 dihydrolipoamide dehydrogenase. | 0.998 |
Shew_1656 | gcvH | Shew_1656 | Shew_3063 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.567 |
Shew_1656 | gcvP | Shew_1656 | Shew_3062 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.651 |
Shew_1656 | lipA | Shew_1656 | Shew_2942 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.551 |
Shew_1656 | lipB | Shew_1656 | Shew_2941 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.537 |
Shew_1927 | Shew_0901 | Shew_1927 | Shew_0901 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes. | PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region. | 0.999 |
Shew_1927 | Shew_3429 | Shew_1927 | Shew_3429 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shm:Shewmr7_3597 dihydrolipoamide dehydrogenase. | 0.997 |
Shew_1927 | Shew_3430 | Shew_1927 | Shew_3430 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.614 |
Shew_1927 | gcvH | Shew_1927 | Shew_3063 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.567 |
Shew_1927 | gcvP | Shew_1927 | Shew_3062 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.651 |
Shew_1927 | lipA | Shew_1927 | Shew_2942 | PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.465 |