STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (135 aa)    
Predicted Functional Partners:
Caur_0121
PFAM: 60 kDa inner membrane insertion protein; KEGG: rrs:RoseRS_3965 60 kDa inner membrane insertion protein.
  
  
 0.984
rpmH
PFAM: ribosomal protein L34; KEGG: rca:Rcas_1423 ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.977
Caur_0398
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
  
 0.955
Caur_0122
PFAM: single-stranded nucleic acid binding R3H domain protein; KEGG: rrs:RoseRS_3964 single-stranded nucleic acid binding R3H domain protein.
 
  
 0.943
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
   
  
 0.875
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  
 0.870
Caur_2961
PFAM: HEAT domain containing protein; RNA binding S1 domain protein; PBS lyase HEAT domain protein repeat-containing protein; KEGG: lsl:LSL_0887 SSU ribosomal protein S1P.
  
  
 0.862
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
    0.861
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
  
 0.852
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
    0.828
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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