STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
Caur_1794
TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: rrs:RoseRS_1548 putative delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.910
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
 
    
 0.866
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
  
 
 0.865
Caur_1698
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: rca:Rcas_2006 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.832
Caur_2070
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: rrs:RoseRS_4385 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.832
Caur_0844
PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: rrs:RoseRS_2715 glutamine synthetase, catalytic region.
    
 0.830
Caur_1448
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: rrs:RoseRS_2983 glutamine synthetase, type I.
    
 0.830
Caur_3395
KEGG: rrs:RoseRS_1047 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
    
 0.830
Caur_1615
Hypothetical protein.
       0.825
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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