node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
def | fmt | Ppha_1788 | Ppha_1787 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.907 |
def | rplI | Ppha_1788 | Ppha_0110 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.845 |
def | rplQ | Ppha_1788 | Ppha_0317 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | PFAM: ribosomal protein L17; KEGG: cph:Cpha266_2395 50S ribosomal protein L17. | 0.853 |
def | rplT | Ppha_1788 | Ppha_0173 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.871 |
def | rplV | Ppha_1788 | Ppha_0294 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.868 |
def | rpsJ | Ppha_1788 | Ppha_0288 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.835 |
def | rpsP | Ppha_1788 | Ppha_1492 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | PFAM: ribosomal protein S16; KEGG: cph:Cpha266_1524 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.833 |
def | rpsT | Ppha_1788 | Ppha_0424 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.842 |
def | rpsU | Ppha_1788 | Ppha_2551 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | PFAM: ribosomal protein S21; KEGG: pvi:Cvib_0348 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. | 0.839 |
def | tig | Ppha_1788 | Ppha_2564 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Trigger factor domain; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.853 |
fmt | def | Ppha_1787 | Ppha_1788 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.907 |
fmt | rpsP | Ppha_1787 | Ppha_1492 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | PFAM: ribosomal protein S16; KEGG: cph:Cpha266_1524 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.423 |
rplI | def | Ppha_0110 | Ppha_1788 | Ribosomal protein L9; Binds to the 23S rRNA. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.845 |
rplI | rplQ | Ppha_0110 | Ppha_0317 | Ribosomal protein L9; Binds to the 23S rRNA. | PFAM: ribosomal protein L17; KEGG: cph:Cpha266_2395 50S ribosomal protein L17. | 0.991 |
rplI | rplT | Ppha_0110 | Ppha_0173 | Ribosomal protein L9; Binds to the 23S rRNA. | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.991 |
rplI | rplV | Ppha_0110 | Ppha_0294 | Ribosomal protein L9; Binds to the 23S rRNA. | Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). | 0.991 |
rplI | rpsJ | Ppha_0110 | Ppha_0288 | Ribosomal protein L9; Binds to the 23S rRNA. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.986 |
rplI | rpsP | Ppha_0110 | Ppha_1492 | Ribosomal protein L9; Binds to the 23S rRNA. | PFAM: ribosomal protein S16; KEGG: cph:Cpha266_1524 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.987 |
rplI | rpsT | Ppha_0110 | Ppha_0424 | Ribosomal protein L9; Binds to the 23S rRNA. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.939 |
rplI | rpsU | Ppha_0110 | Ppha_2551 | Ribosomal protein L9; Binds to the 23S rRNA. | PFAM: ribosomal protein S21; KEGG: pvi:Cvib_0348 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. | 0.944 |