STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDE1NudE neurodevelopment protein 1. (331 aa)    
Predicted Functional Partners:
LOC102800241
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 
 0.801
LOC102799993
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 
 0.801
LOC102785895
NudC nuclear distribution protein.
     
 0.785
LOC102797555
NudC domain containing 3.
     
 0.707
LOC102789250
NudC domain containing 2.
     
 0.707
LOC102797615
Uncharacterized protein.
    
 
 0.700
ENSNBRP00000017171
BUB3 mitotic checkpoint protein.
     
 0.696
ENSNBRP00000000848
Uncharacterized protein.
    
 
 0.675
LOC102799090
Amino_oxidase domain-containing protein.
    
 
 0.675
ENSNBRP00000012130
WD_REPEATS_REGION domain-containing protein.
    
 
 0.675
Your Current Organism:
Neolamprologus brichardi
NCBI taxonomy Id: 32507
Other names: Lamprologus brichardi, N. brichardi, lyretail cichlid
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.