node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sbal_1178 | Sbal_3911 | Sbal_1178 | Sbal_3911 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: shm:Shewmr7_2954 glutamate synthase (ferredoxin). | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | 0.902 |
Sbal_1178 | Sbal_4027 | Sbal_1178 | Sbal_4027 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: shm:Shewmr7_2954 glutamate synthase (ferredoxin). | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | 0.516 |
Sbal_1178 | gcvH | Sbal_1178 | Sbal_0618 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: shm:Shewmr7_2954 glutamate synthase (ferredoxin). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.884 |
Sbal_1178 | gcvP | Sbal_1178 | Sbal_0619 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: shm:Shewmr7_2954 glutamate synthase (ferredoxin). | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.939 |
Sbal_1178 | gcvT | Sbal_1178 | Sbal_0617 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: shm:Shewmr7_2954 glutamate synthase (ferredoxin). | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.890 |
Sbal_1178 | glyA | Sbal_1178 | Sbal_3162 | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: shm:Shewmr7_2954 glutamate synthase (ferredoxin). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.427 |
Sbal_1918 | Sbal_3911 | Sbal_1918 | Sbal_3911 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | 0.406 |
Sbal_1918 | gcvP | Sbal_1918 | Sbal_0619 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.959 |
Sbal_1918 | glyA | Sbal_1918 | Sbal_3162 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.459 |
Sbal_3011 | Sbal_4027 | Sbal_3011 | Sbal_4027 | L-threonine aldolase; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO3338 L-allo-threonine aldolase. | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | 0.932 |
Sbal_3011 | gcvP | Sbal_3011 | Sbal_0619 | L-threonine aldolase; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO3338 L-allo-threonine aldolase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.947 |
Sbal_3011 | glyA | Sbal_3011 | Sbal_3162 | L-threonine aldolase; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO3338 L-allo-threonine aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.942 |
Sbal_3011 | kbl | Sbal_3011 | Sbal_0058 | L-threonine aldolase; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO3338 L-allo-threonine aldolase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.918 |
Sbal_3911 | Sbal_1178 | Sbal_3911 | Sbal_1178 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: shm:Shewmr7_2954 glutamate synthase (ferredoxin). | 0.902 |
Sbal_3911 | Sbal_1918 | Sbal_3911 | Sbal_1918 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.406 |
Sbal_3911 | Sbal_4027 | Sbal_3911 | Sbal_4027 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | 0.905 |
Sbal_3911 | gcvH | Sbal_3911 | Sbal_0618 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.984 |
Sbal_3911 | gcvP | Sbal_3911 | Sbal_0619 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.954 |
Sbal_3911 | gcvT | Sbal_3911 | Sbal_0617 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.966 |
Sbal_3911 | glyA | Sbal_3911 | Sbal_3162 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shn:Shewana3_0428 dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.930 |