STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fadI3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa)    
Predicted Functional Partners:
fadB
3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 0.999
fadJ
3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 0.999
Sbal_2244
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: she:Shewmr4_2049 acyl-CoA dehydrogenase domain protein.
 
 0.980
Sbal_2306
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: shm:Shewmr7_2223 acyl-CoA dehydrogenase domain protein.
 
 0.980
Sbal_2832
hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase; KEGG: she:Shewmr4_2326 pyruvate carboxyltransferase.
  
 
 0.935
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.931
Sbal_0533
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shn:Shewana3_0572 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.927
Sbal_1495
KEGG: shm:Shewmr7_2664 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 
0.925
Sbal_3582
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shn:Shewana3_0721 enoyl-CoA hydratase/isomerase.
 
 0.924
fadA
3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
  
 
0.921
Your Current Organism:
Shewanella baltica
NCBI taxonomy Id: 325240
Other names: S. baltica OS155, Shewanella baltica OS155, Shewanella baltica str. OS155, Shewanella baltica strain OS155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.