node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_0612 | Sama_1814 | Sama_0612 | Sama_1814 | KEGG: son:SO0968 D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | KEGG: son:SO2491 pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.934 |
Sama_0612 | Sama_2019 | Sama_0612 | Sama_2019 | KEGG: son:SO0968 D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | 0.814 |
Sama_0612 | Sama_2072 | Sama_0612 | Sama_2072 | KEGG: son:SO0968 D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.914 |
Sama_0612 | leuA | Sama_0612 | Sama_0335 | KEGG: son:SO0968 D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.817 |
Sama_0612 | leuC | Sama_0612 | Sama_0337 | KEGG: son:SO0968 D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.811 |
Sama_0612 | leuD | Sama_0612 | Sama_0338 | KEGG: son:SO0968 D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.803 |
Sama_1814 | Sama_0612 | Sama_1814 | Sama_0612 | KEGG: son:SO2491 pyruvate kinase II; Belongs to the pyruvate kinase family. | KEGG: son:SO0968 D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.934 |
Sama_1814 | Sama_2019 | Sama_1814 | Sama_2019 | KEGG: son:SO2491 pyruvate kinase II; Belongs to the pyruvate kinase family. | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | 0.800 |
Sama_1814 | Sama_2072 | Sama_1814 | Sama_2072 | KEGG: son:SO2491 pyruvate kinase II; Belongs to the pyruvate kinase family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.933 |
Sama_1814 | leuA | Sama_1814 | Sama_0335 | KEGG: son:SO2491 pyruvate kinase II; Belongs to the pyruvate kinase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.820 |
Sama_1814 | leuC | Sama_1814 | Sama_0337 | KEGG: son:SO2491 pyruvate kinase II; Belongs to the pyruvate kinase family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.819 |
Sama_1814 | leuD | Sama_1814 | Sama_0338 | KEGG: son:SO2491 pyruvate kinase II; Belongs to the pyruvate kinase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.841 |
Sama_2019 | Sama_0612 | Sama_2019 | Sama_0612 | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | KEGG: son:SO0968 D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.814 |
Sama_2019 | Sama_1814 | Sama_2019 | Sama_1814 | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | KEGG: son:SO2491 pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.800 |
Sama_2019 | Sama_2072 | Sama_2019 | Sama_2072 | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.802 |
Sama_2019 | Sama_2423 | Sama_2019 | Sama_2423 | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | KEGG: sdn:Sden_2561 isocitrate dehydrogenase (NAD+). | 0.715 |
Sama_2019 | ilvC | Sama_2019 | Sama_3282 | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.996 |
Sama_2019 | ilvD | Sama_2019 | Sama_3279 | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | KEGG: son:SO4345 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.848 |
Sama_2019 | leuA | Sama_2019 | Sama_0335 | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.953 |
Sama_2019 | leuB | Sama_2019 | Sama_0336 | KEGG: sdn:Sden_2123 acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.982 |