node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_2246 | fmt | Sama_2246 | Sama_0042 | Methionyl-tRNA formyltransferase; KEGG: pca:Pcar_1117 hypothetical protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.925 |
Sama_2246 | folD | Sama_2246 | Sama_1222 | Methionyl-tRNA formyltransferase; KEGG: pca:Pcar_1117 hypothetical protein. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.953 |
Sama_2246 | gcvT | Sama_2246 | Sama_2721 | Methionyl-tRNA formyltransferase; KEGG: pca:Pcar_1117 hypothetical protein. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.913 |
Sama_2246 | glyA | Sama_2246 | Sama_1014 | Methionyl-tRNA formyltransferase; KEGG: pca:Pcar_1117 hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.910 |
Sama_2246 | purN | Sama_2246 | Sama_2098 | Methionyl-tRNA formyltransferase; KEGG: pca:Pcar_1117 hypothetical protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.924 |
Sama_2726 | folD | Sama_2726 | Sama_1222 | KEGG: son:SO0774 5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.941 |
Sama_2726 | glyA | Sama_2726 | Sama_1014 | KEGG: son:SO0774 5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.430 |
Sama_2726 | purN | Sama_2726 | Sama_2098 | KEGG: son:SO0774 5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.927 |
Sama_3169 | fhs | Sama_3169 | Sama_3146 | KEGG: son:SO4054 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.456 |
Sama_3169 | folD | Sama_3169 | Sama_1222 | KEGG: son:SO4054 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.941 |
Sama_3169 | gcvT | Sama_3169 | Sama_2721 | KEGG: son:SO4054 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.943 |
Sama_3169 | glyA | Sama_3169 | Sama_1014 | KEGG: son:SO4054 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.953 |
Sama_3169 | purN | Sama_3169 | Sama_2098 | KEGG: son:SO4054 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.431 |
fhs | Sama_3169 | Sama_3146 | Sama_3169 | KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | KEGG: son:SO4054 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.456 |
fhs | folD | Sama_3146 | Sama_1222 | KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.996 |
fhs | gcvT | Sama_3146 | Sama_2721 | KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.953 |
fhs | glyA | Sama_3146 | Sama_1014 | KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.968 |
fhs | purH | Sama_3146 | Sama_0395 | KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase; KEGG: son:SO0442 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.985 |
fhs | purN | Sama_3146 | Sama_2098 | KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.968 |
fhs | purU | Sama_3146 | Sama_1134 | KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.585 |