node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_0376 | Sama_0377 | Sama_0376 | Sama_0377 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | 0.999 |
Sama_0376 | Sama_1427 | Sama_0376 | Sama_1427 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: son:SO1930 2-oxoglutarate dehydrogenase E1 component. | 0.970 |
Sama_0376 | Sama_1711 | Sama_0376 | Sama_1711 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: son:SO2341 alpha keto acid dehydrogenase complex, E2 component. | 0.589 |
Sama_0376 | Sama_3543 | Sama_0376 | Sama_3543 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: son:SO4702 glutathione reductase. | 0.938 |
Sama_0376 | sucC | Sama_0376 | Sama_1429 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.948 |
Sama_0376 | sucD | Sama_0376 | Sama_1430 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.932 |
Sama_0377 | Sama_0376 | Sama_0377 | Sama_0376 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
Sama_0377 | Sama_0857 | Sama_0377 | Sama_0857 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | 0.902 |
Sama_0377 | Sama_1427 | Sama_0377 | Sama_1427 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | KEGG: son:SO1930 2-oxoglutarate dehydrogenase E1 component. | 0.994 |
Sama_0377 | Sama_1428 | Sama_0377 | Sama_1428 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.998 |
Sama_0377 | Sama_1711 | Sama_0377 | Sama_1711 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | KEGG: son:SO2341 alpha keto acid dehydrogenase complex, E2 component. | 0.997 |
Sama_0377 | sucC | Sama_0377 | Sama_1429 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.604 |
Sama_0377 | sucD | Sama_0377 | Sama_1430 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.470 |
Sama_0857 | Sama_0377 | Sama_0857 | Sama_0377 | KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | 0.902 |
Sama_0857 | Sama_1427 | Sama_0857 | Sama_1427 | KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | KEGG: son:SO1930 2-oxoglutarate dehydrogenase E1 component. | 0.911 |
Sama_0857 | Sama_2059 | Sama_0857 | Sama_2059 | KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | KEGG: son:SO2629 isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. | 0.900 |
Sama_0857 | Sama_2423 | Sama_0857 | Sama_2423 | KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | KEGG: sdn:Sden_2561 isocitrate dehydrogenase (NAD+). | 0.919 |
Sama_0857 | Sama_3543 | Sama_0857 | Sama_3543 | KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | KEGG: son:SO4702 glutathione reductase. | 0.532 |
Sama_0857 | sucC | Sama_0857 | Sama_1429 | KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.547 |
Sama_0857 | sucD | Sama_0857 | Sama_1430 | KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.644 |