node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_0758 | Sama_0894 | Sama_0758 | Sama_0894 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: son:SO1362 prephenate dehydrogenase / chorismate mutase. | 0.547 |
Sama_0758 | Sama_1242 | Sama_0758 | Sama_1242 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: son:SO1812 methionine gamma-lyase. | 0.972 |
Sama_0758 | Sama_1583 | Sama_0758 | Sama_1583 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: sdn:Sden_1720 GAF domain-containing protein. | 0.900 |
Sama_0758 | Sama_1805 | Sama_0758 | Sama_1805 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminotransferase; KEGG: son:SO2350 aspartate aminotransferase. | 0.910 |
Sama_0758 | hisC | Sama_0758 | Sama_1943 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: son:SO2072 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.458 |
Sama_0758 | metK | Sama_0758 | Sama_2760 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.958 |
Sama_0894 | Sama_0758 | Sama_0894 | Sama_0758 | KEGG: son:SO1362 prephenate dehydrogenase / chorismate mutase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.547 |
Sama_0894 | Sama_0898 | Sama_0894 | Sama_0898 | KEGG: son:SO1362 prephenate dehydrogenase / chorismate mutase. | KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.999 |
Sama_0894 | Sama_1568 | Sama_0894 | Sama_1568 | KEGG: son:SO1362 prephenate dehydrogenase / chorismate mutase. | KEGG: sdn:Sden_2163 4-hydroxyphenylpyruvate dioxygenase. | 0.451 |
Sama_0894 | Sama_1733 | Sama_0894 | Sama_1733 | KEGG: son:SO1362 prephenate dehydrogenase / chorismate mutase. | Aminotransferase; KEGG: sfr:Sfri_2126 aspartate transaminase. | 0.946 |
Sama_0894 | Sama_1805 | Sama_0894 | Sama_1805 | KEGG: son:SO1362 prephenate dehydrogenase / chorismate mutase. | Aminotransferase; KEGG: son:SO2350 aspartate aminotransferase. | 0.946 |
Sama_0894 | hisC | Sama_0894 | Sama_1943 | KEGG: son:SO1362 prephenate dehydrogenase / chorismate mutase. | KEGG: son:SO2072 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.992 |
Sama_0898 | Sama_0894 | Sama_0898 | Sama_0894 | KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase. | KEGG: son:SO1362 prephenate dehydrogenase / chorismate mutase. | 0.999 |
Sama_0898 | Sama_1242 | Sama_0898 | Sama_1242 | KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase. | KEGG: son:SO1812 methionine gamma-lyase. | 0.496 |
Sama_0898 | Sama_1568 | Sama_0898 | Sama_1568 | KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase. | KEGG: sdn:Sden_2163 4-hydroxyphenylpyruvate dioxygenase. | 0.402 |
Sama_0898 | Sama_1733 | Sama_0898 | Sama_1733 | KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase. | Aminotransferase; KEGG: sfr:Sfri_2126 aspartate transaminase. | 0.947 |
Sama_0898 | Sama_1805 | Sama_0898 | Sama_1805 | KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase. | Aminotransferase; KEGG: son:SO2350 aspartate aminotransferase. | 0.947 |
Sama_0898 | Sama_2222 | Sama_0898 | Sama_2222 | KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase. | KEGG: son:SO1666 phenylalanine-4-hydroxylase. | 0.935 |
Sama_0898 | hisC | Sama_0898 | Sama_1943 | KEGG: son:SO1367 prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase. | KEGG: son:SO2072 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.968 |
Sama_1242 | Sama_0758 | Sama_1242 | Sama_0758 | KEGG: son:SO1812 methionine gamma-lyase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.972 |