node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABB43853.1 | hisA | Suden_0574 | Suden_1673 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.675 |
ABB43853.1 | hisB | Suden_0574 | Suden_1080 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | Imidazoleglycerol-phosphate dehydratase. | 0.749 |
ABB43853.1 | hisC | Suden_0574 | Suden_0471 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | Histidinol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.752 |
ABB43853.1 | hisD | Suden_0574 | Suden_0497 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.734 |
ABB43853.1 | hisF | Suden_0574 | Suden_2091 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.664 |
ABB43853.1 | hisG | Suden_0574 | Suden_0889 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.618 |
ABB43853.1 | hisH | Suden_0574 | Suden_1674 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.719 |
ABB43853.1 | hisI | Suden_0574 | Suden_1875 | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | phosphoribosyl-ATP pyrophosphatase / phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.970 |
ABB44952.1 | hisA | Suden_1675 | Suden_1673 | Conserved hypothetical protein. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.791 |
ABB44952.1 | hisH | Suden_1675 | Suden_1674 | Conserved hypothetical protein. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.818 |
guaA | hisA | Suden_0422 | Suden_1673 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.795 |
guaA | hisF | Suden_0422 | Suden_2091 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.545 |
guaA | hisH | Suden_0422 | Suden_1674 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.556 |
hisA | ABB43853.1 | Suden_1673 | Suden_0574 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase. | 0.675 |
hisA | ABB44952.1 | Suden_1673 | Suden_1675 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Conserved hypothetical protein. | 0.791 |
hisA | guaA | Suden_1673 | Suden_0422 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.795 |
hisA | hisB | Suden_1673 | Suden_1080 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Imidazoleglycerol-phosphate dehydratase. | 0.986 |
hisA | hisC | Suden_1673 | Suden_0471 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Histidinol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.936 |
hisA | hisD | Suden_1673 | Suden_0497 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.983 |
hisA | hisF | Suden_1673 | Suden_2091 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.995 |