node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FRAAL0107 | guaA | FRAAL0107 | FRAAL1150 | Hypothetical protein; No homology to any previously reported sequences. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.513 |
FRAAL0107 | pdxH | FRAAL0107 | FRAAL0106 | Hypothetical protein; No homology to any previously reported sequences. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.696 |
FRAAL1839 | FRAAL4777 | FRAAL1839 | FRAAL4777 | Putative oxidoreductase, NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.906 |
FRAAL1839 | pdxH | FRAAL1839 | FRAAL0106 | Putative oxidoreductase, NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.903 |
FRAAL4777 | FRAAL1839 | FRAAL4777 | FRAAL1839 | Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative oxidoreductase, NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.906 |
FRAAL4777 | pdxH | FRAAL4777 | FRAAL0106 | Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.903 |
gcvP | guaA | FRAAL6434 | FRAAL1150 | Glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.826 |
gcvP | pdxH | FRAAL6434 | FRAAL0106 | Glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.581 |
guaA | FRAAL0107 | FRAAL1150 | FRAAL0107 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; No homology to any previously reported sequences. | 0.513 |
guaA | gcvP | FRAAL1150 | FRAAL6434 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.826 |
guaA | pdx1 | FRAAL1150 | FRAAL2136 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.584 |
guaA | pdxH | FRAAL1150 | FRAAL0106 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.557 |
guaA | pdxT | FRAAL1150 | FRAAL2137 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Putative glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.577 |
guaA | pyrB | FRAAL1150 | FRAAL5238 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Aspartate carbamoyltransferase (Aspartate transcarbamylase) (ATCase); Function of strongly homologous gene; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.731 |
guaA | ribA | FRAAL1150 | FRAAL5220 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein ribA [Includes: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.902 |
pdx1 | guaA | FRAAL2136 | FRAAL1150 | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.584 |
pdx1 | pdxH | FRAAL2136 | FRAAL0106 | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.956 |
pdx1 | pdxT | FRAAL2136 | FRAAL2137 | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Putative glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.999 |
pdxH | FRAAL0107 | FRAAL0106 | FRAAL0107 | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Hypothetical protein; No homology to any previously reported sequences. | 0.696 |
pdxH | FRAAL1839 | FRAAL0106 | FRAAL1839 | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative oxidoreductase, NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.903 |