node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FRAAL0949 | mshA | FRAAL0949 | FRAAL0950 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.835 |
FRAAL1861 | cysS2 | FRAAL1861 | FRAAL2858 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.674 |
FRAAL1861 | mca | FRAAL1861 | FRAAL6212 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | 0.787 |
FRAAL1861 | mshA | FRAAL1861 | FRAAL0950 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.654 |
FRAAL1861 | mshB1 | FRAAL1861 | FRAAL3175 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative N-acetylglucosaminylphosphatidylinositol deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.775 |
FRAAL1861 | mshB2 | FRAAL1861 | FRAAL6132 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 2; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.774 |
FRAAL1861 | mshD | FRAAL1861 | FRAAL0935 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. | 0.793 |
FRAAL6860 | mshA | FRAAL6860 | FRAAL0950 | Putative 1L-myo-inositol-1-phosphate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.627 |
cysS2 | FRAAL1861 | FRAAL2858 | FRAAL1861 | Cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.674 |
cysS2 | mca | FRAAL2858 | FRAAL6212 | Cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | 0.876 |
cysS2 | mshA | FRAAL2858 | FRAAL0950 | Cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | Putative glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.753 |
cysS2 | mshB1 | FRAAL2858 | FRAAL3175 | Cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | Putative N-acetylglucosaminylphosphatidylinositol deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.833 |
cysS2 | mshB2 | FRAAL2858 | FRAAL6132 | Cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 2; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.831 |
cysS2 | mshD | FRAAL2858 | FRAAL0935 | Cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. | 0.972 |
glgB | mshA | FRAAL5902 | FRAAL0950 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Putative glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.599 |
glgB | treZ | FRAAL5902 | FRAAL2116 | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Malto-oligosyltrehalose trehalohydrolase; Function of strongly homologous gene; enzyme. | 0.495 |
mca | FRAAL1861 | FRAAL6212 | FRAAL1861 | Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.787 |
mca | cysS2 | FRAAL6212 | FRAAL2858 | Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | Cysteinyl-tRNA synthetase 2 (Cysteine--tRNA ligase 2); Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.876 |
mca | mshA | FRAAL6212 | FRAAL0950 | Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | Putative glycosyl transferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.814 |
mca | mshD | FRAAL6212 | FRAAL0935 | Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. | 0.896 |