node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FRAAL2142 | FRAAL4584 | FRAAL2142 | FRAAL4584 | Hypothetical protein; No homology to any previously reported sequences. | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.977 |
FRAAL2142 | FRAAL6881 | FRAAL2142 | FRAAL6881 | Hypothetical protein; No homology to any previously reported sequences. | Putative Membrane protein oxaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.930 |
FRAAL2142 | ffh | FRAAL2142 | FRAAL5793 | Hypothetical protein; No homology to any previously reported sequences. | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.971 |
FRAAL2142 | ftsY | FRAAL2142 | FRAAL5795 | Hypothetical protein; No homology to any previously reported sequences. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.972 |
FRAAL2142 | secA | FRAAL2142 | FRAAL1306 | Hypothetical protein; No homology to any previously reported sequences. | Preprotein translocase, ATPase secretion component (General Secretory Pathway); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.972 |
FRAAL2142 | secD | FRAAL2142 | FRAAL2144 | Hypothetical protein; No homology to any previously reported sequences. | Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.961 |
FRAAL2142 | secY | FRAAL2142 | FRAAL1101 | Hypothetical protein; No homology to any previously reported sequences. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.970 |
FRAAL4584 | FRAAL2142 | FRAAL4584 | FRAAL2142 | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; No homology to any previously reported sequences. | 0.977 |
FRAAL4584 | FRAAL6881 | FRAAL4584 | FRAAL6881 | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Putative Membrane protein oxaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.976 |
FRAAL4584 | ffh | FRAAL4584 | FRAAL5793 | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.961 |
FRAAL4584 | ftsY | FRAAL4584 | FRAAL5795 | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.984 |
FRAAL4584 | secA | FRAAL4584 | FRAAL1306 | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, ATPase secretion component (General Secretory Pathway); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.996 |
FRAAL4584 | secD | FRAAL4584 | FRAAL2144 | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.928 |
FRAAL4584 | secY | FRAAL4584 | FRAAL1101 | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.996 |
FRAAL6881 | FRAAL2142 | FRAAL6881 | FRAAL2142 | Putative Membrane protein oxaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Hypothetical protein; No homology to any previously reported sequences. | 0.930 |
FRAAL6881 | FRAAL4584 | FRAAL6881 | FRAAL4584 | Putative Membrane protein oxaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.976 |
FRAAL6881 | ffh | FRAAL6881 | FRAAL5793 | Putative Membrane protein oxaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.961 |
FRAAL6881 | ftsY | FRAAL6881 | FRAAL5795 | Putative Membrane protein oxaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.959 |
FRAAL6881 | ftsZ | FRAAL6881 | FRAAL2200 | Putative Membrane protein oxaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.415 |
FRAAL6881 | gyrA | FRAAL6881 | FRAAL0009 | Putative Membrane protein oxaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA gyrase, subunit A, type II topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP- [...] | 0.634 |