STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRAAL2606Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (156 aa)    
Predicted Functional Partners:
FRAAL6729
Putative amino acid ABC transporter amino acid-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter.
  
    0.809
FRAAL1802
Putative pyruvate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the TPP enzyme family.
  
  
 0.741
FRAAL2602
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.560
FRAAL0006
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.513
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
  
 0.490
dnaK
Chaperone Hsp70 in DNA biosynthesis/cell division; Function of strongly homologous gene; molecular chaperone; Belongs to the heat shock protein 70 family.
  
  
 0.482
FRAAL2022
Hypothetical protein; No homology to any previously reported sequences.
  
    0.470
FRAAL6648
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.470
FRAAL1747
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
    0.457
grpE
Hsp 24 nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several roun [...]
       0.448
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.