STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDPutative O-sialoglycoprotein endopeptidase, with actin-like ATPase domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (356 aa)    
Predicted Functional Partners:
FRAAL1128
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
 
0.996
FRAAL3777
Putative kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.976
FRAAL1127
Putative ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
 
 0.939
ureG
Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
     
 0.862
FRAAL6285
16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; Function of strongly homologous gene; enzyme.
 
  
 0.835
pheT
Phenylalanine tRNA synthetase, beta-subunit; Function of strongly homologous gene; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.769
inf
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
  
 0.707
ychF
Putative GTP-binding protein with nucleoside triP hydrolase domain; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.707
recO
DNA repair protein recO (Recombination protein O); Involved in DNA repair and RecF pathway recombination.
     
 0.697
asd
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of strongly homologous gene; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.696
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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