STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family. (400 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
gapA
Glyceraldehyde-3-phosphate dehydrogenase A; Function of strongly homologous gene; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.999
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.994
gpmA
Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.988
pykA
Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family.
 
 
 0.950
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.949
pgi
Glucosephosphate isomerase; Function of strongly homologous gene; enzyme; Belongs to the GPI family.
  
 
 0.921
rpe
D-ribulose-5-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family.
 
 
 0.881
FRAAL3253
Pyruvate-flavodoxin oxidoreductase; Function of strongly homologous gene; enzyme.
  
  
 0.832
FRAAL1273
Hypothetical protein; No homology to any previously reported sequences.
  
 
 0.792
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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