node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
frr | guaA | FRAAL5778 | FRAAL1150 | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.700 |
frr | hpt | FRAAL5778 | FRAAL6587 | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Hypoxanthine phosphoribosyltransferase (partial match); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.475 |
frr | pheT | FRAAL5778 | FRAAL5210 | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Phenylalanine tRNA synthetase, beta-subunit; Function of strongly homologous gene; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.863 |
frr | prfA | FRAAL5778 | FRAAL5945 | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.973 |
frr | prfB | FRAAL5778 | FRAAL1352 | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.943 |
frr | pth | FRAAL5778 | FRAAL6266 | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.679 |
frr | rplM | FRAAL5778 | FRAAL1114 | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.990 |
frr | rplY | FRAAL5778 | FRAAL6267 | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.827 |
guaA | frr | FRAAL1150 | FRAAL5778 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.700 |
guaA | hpt | FRAAL1150 | FRAAL6587 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Hypoxanthine phosphoribosyltransferase (partial match); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.626 |
guaA | pheT | FRAAL1150 | FRAAL5210 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phenylalanine tRNA synthetase, beta-subunit; Function of strongly homologous gene; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.971 |
guaA | prfB | FRAAL1150 | FRAAL1352 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.435 |
guaA | pth | FRAAL1150 | FRAAL6266 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.762 |
guaA | rplM | FRAAL1150 | FRAAL1114 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.833 |
guaA | rplY | FRAAL1150 | FRAAL6267 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.575 |
guaA | ychF | FRAAL1150 | FRAAL6139 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Putative GTP-binding protein with nucleoside triP hydrolase domain; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.797 |
hpt | frr | FRAAL6587 | FRAAL5778 | Hypoxanthine phosphoribosyltransferase (partial match); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.475 |
hpt | guaA | FRAAL6587 | FRAAL1150 | Hypoxanthine phosphoribosyltransferase (partial match); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.626 |
hpt | mfd | FRAAL6587 | FRAAL6237 | Hypoxanthine phosphoribosyltransferase (partial match); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Transcription-repair coupling factor (TRCF); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.570 |
hpt | pheT | FRAAL6587 | FRAAL5210 | Hypoxanthine phosphoribosyltransferase (partial match); Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | Phenylalanine tRNA synthetase, beta-subunit; Function of strongly homologous gene; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.629 |