STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantoate-beta-alanine ligase (Pantothenate synthetase) (Pantoate activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (294 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase (partial match); Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 0.993
coaX
Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
  
 
 0.956
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.955
gadB
Glutamate decarboxylase, PLP-dependent, isozyme beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the group II decarboxylase family.
  
 
 0.931
coaA
Pantothenate kinase (N-terminal part); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.908
coaA-2
Pantothenate kinase (C-terminal part); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.908
FRAAL1415
Putative nitrilase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
    
 0.906
FRAAL1423
Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.903
cmk
Cytidylate kinase (CK) (Cytidine monophosphate kinase) (CMP kinase); Function of strongly homologous gene; enzyme.
      0.903
gabT
4-aminobutyrate aminotransferase, PLP-dependent; Function of strongly homologous gene; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.903
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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